LL-37 5 mg
$26.40
LL-37 5 mg – Peptide Hubs
LL-37 is a naturally occurring antimicrobial peptide (AMP) that plays a vital role in the human innate immune system. As the only known human cathelicidin peptide, LL-37 is involved in bacterial, viral, and fungal defense as well as in tissue healing and inflammation modulation. Peptide Hubs provides high-purity LL-37 in a 5 mg lyophilized vial for use in immune, dermatological, and regenerative research.
Mechanism of Action
LL-37 acts by disrupting the membranes of pathogens through electrostatic interactions, leading to bacterial cell lysis. Beyond antimicrobial activity, LL-37 also influences chemotaxis, angiogenesis, and epithelial cell proliferation, making it relevant in wound healing and immune surveillance models. For more information, see this NIH article on LL-37 functions in immunity.
Research Applications
- Broad-spectrum antimicrobial activity studies
- Skin repair and chronic wound healing models
- Respiratory epithelial defense research (e.g., sinusitis, lung injury)
- Modulation of inflammatory cytokines and immune response
LL-37 is often co-researched with GHK Basic for epithelial and collagen regeneration, or Chonluten for respiratory inflammation studies. Some researchers explore combined protocols with L-Glutathione for oxidative defense, or B7-33 for tissue remodeling in fibrotic conditions.